EPITALON

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide modeled on pineal extracts investigated for its role in circadian regulation and cellular homeostasis. Research centers on epigenetic and neuroendocrine interfaces, including studies of sleep–wake biology, pineal–hypothalamic signaling, and biomarkers associated with replicative lifespan in vitro and in translational models.

Pathways: Literature reports examine Epitalon’s effects on pineal and hypothalamic activity with downstream modulation of melatonin secretion and circadian gene programs (e.g., PER/CLOCK axes). In cell models, investigations include telomere biology (telomerase activity/readouts), genome maintenance signals, and oxidative-stress response.
Functional Notes: Ongoing studies probe redox homeostasis, mitochondrial efficiency, and proteostasis networks linked to cellular adaptation during replicative stress.

Circadian and sleep–wake regulation • Pineal–hypothalamic endocrine mapping • Telomere-related readouts in cell culture • Oxidative-stress and mitochondrial function assays • Exploratory models of cellular longevity and genomic maintenance.

Revitalized Health peptides are produced under cGMP-aligned conditions with pharmaceutical-grade inputs. Each Epitalon lot is confirmed at ≥99% purity by HPLC with identity verified via LC-MS/MS. Lots undergo appearance/solubility checks and microbial/endotoxin screening to research-grade specifications. Batch-level Certificates of Analysis document methods, parameters, and results for full traceability.

Store lyophilized vials at 2–8 °C, protected from light and moisture. Following reconstitution with bacteriostatic water, maintain at 2–8 °C and utilize within 20 days. Avoid repeated freeze–thaw cycles to preserve peptide integrity and target-engagement fidelity.

For laboratory research use only. Not intended for human consumption, therapeutic, or diagnostic application. Supplied exclusively to qualified professionals conducting controlled scientific investigations.