GHK-CU 50MG

GHK-Cu (glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring copper-binding tripeptide investigated for roles in dermal remodeling, angiogenic signaling, and anti-inflammatory modulation. The 50 mg research format supports controlled studies of extracellular-matrix (ECM) renewal, cellular migration, and redox-metal homeostasis in skin, connective-tissue, and wound models.

Copper Delivery: GHK chelates Cu²⁺, facilitating bioavailable copper transport to cuproenzymes (e.g., lysyl oxidase, superoxide dismutase) implicated in crosslinking and redox defense.
ECM Programs: Literature reports upregulation of collagen and glycosaminoglycan synthesis with concurrent modulation of MMPs/TIMPs, supporting balanced matrix turnover and re-epithelialization.
Cell Signaling: In vitro models evaluate pathways linked to integrin/focal-adhesion dynamics, TGF-β remodeling cues, and cytokine tone reduction in inflammatory microenvironments.
Angiogenesis & Repair: Pro-migratory and pro-angiogenic effects are profiled via endothelial and fibroblast assays that index neovascularization and tissue closure kinetics.

Dermal/wound-healing models • Scar modulation and ECM remodeling • Copper homeostasis and antioxidant defense (SOD activity) • Keratinocyte/fibroblast migration assays • Collagen/GAG synthesis readouts • Angiogenesis and microvascular integrity studies.

Revitalized Health peptides are produced under cGMP-aligned conditions with pharmaceutical-grade inputs. Each GHK-Cu lot is confirmed at ≥99% purity by HPLC with structure/identity verified via LC-MS/MS. Appearance and solubility are checked; microbial and endotoxin limits are monitored to research-grade specifications. Batch Certificates of Analysis provide full analytical parameters and results.

Store lyophilized GHK-Cu at 2–8 °C, protected from light and moisture. Following reconstitution with suitable diluent, maintain at 2–8 °C and utilize within 20 days. Avoid repeated freeze–thaw cycles. Use low-metal, low-binding plastics/glassware to minimize trace-metal exchange during experiments.

For laboratory research use only. Not intended for human consumption, therapeutic, or diagnostic application. Supplied exclusively to qualified professionals conducting controlled scientific investigations.

Target: Copper(II) delivery via tripeptide Gly-His-Lys; interacts with ECM/cell-surface binding sites.
Mode: Chelates Cu²⁺ to form GHK-Cu, supporting copper-dependent enzymes (e.g., lysyl oxidase, SOD). Promotes ECM remodeling (↑ collagen I/III, elastin, glycosaminoglycans), pro-repair gene programs, angiogenic support, and modulation of inflammatory cytokines (↓ IL-1β/TNF-α signatures in models). In hair/skin models, influences dermal papilla activity and keratinocyte/fibroblast signaling.
Analytics: Identity/purity by HPLC and LC-MS; copper loading by UV-Vis (d–d band) and ICP-MS; stability/metal exchange assays; in-vitro readouts: procollagen C-peptide ELISA, MMP/TIMP balance, SOD activity, ROS assays; dermal imaging or ultrasound for thickness/elasticity in cosmetic studies. Safety monitoring: local dermal tolerance; systemic copper indices where relevant.