Research Overview

Kisspeptin (KISS-1 Peptide) 10mg is a neuropeptide ligand for the G-protein–coupled receptor GPR54 (KISS1R), extensively studied for its pivotal role in reproductive-axis signaling. Research models examine Kisspeptin’s involvement in hypothalamic GnRH regulation, endocrine communication, and neurobehavioral pathways that influence fertility, hormone release, and metabolic–reproductive crosstalk.

Per vial composition: Kisspeptin 10 mg (lyophilized for reconstitution in research environments).

Mechanism of Action

GPR54 Activation: Kisspeptin binds to the KISS1R receptor, stimulating hypothalamic GnRH release, which sequentially influences LH and FSH output in controlled endocrine models.
Reproductive-Axis Modulation: Studies evaluate Kisspeptin’s impact on puberty initiation, gonadal hormone production, and neuroendocrine reproductive feedback systems.
Neurobehavioral & Metabolic Links: Research explores signaling connections between Kisspeptin, stress responses, energy balance, sexual-behavior circuits, and metabolic–reproductive hormonal coordination.

Research Applications

GnRH and reproductive-hormone modeling • Endocrine-axis and fertility research • Neuroendocrine pathway assays • Kisspeptin receptor (KISS1R) signaling studies • Puberty and hormone-release frameworks • Behavioral neuroendocrine models • PK/PD evaluation of Kisspeptin and related analogs.

Purity & Quality Assurance

Revitalized Health research peptides are produced under cGMP-aligned conditions with pharmaceutical-grade raw materials. Each Kisspeptin 10mg lot is confirmed at ≥99% purity via HPLC, with structural identity validated using LC-MS/MS. All batches undergo microbial/endotoxin screening, solubility confirmation, and visual inspection. Batch-specific Certificates of Analysis provide full analytical detail for research traceability.

Storage & Stability

Store lyophilized Kisspeptin 10mg at 2–8 °C, protected from light and moisture. After reconstitution with bacteriostatic water, maintain at 2–8 °C and utilize within 20 days. Avoid repeated freeze–thaw cycles to preserve peptide stability, receptor-binding fidelity, and experimental consistency.

Research Disclaimer

For laboratory research use only. Not intended for human consumption, therapeutic use, or diagnostic application. Distributed exclusively to qualified professionals conducting controlled scientific studies.

Formulated as Kisspeptin 10mg for research use only. Batch analytics available upon request. Not medical advice.

Mechanism Strength
94/100
KISS1 → GnRH stimulation • reproductive-axis driver
Reproductive Axis Activation
90/100
↑ GnRH → LH/FSH pulse modulation
Evidence Level
85/100
Strong data in fertility & endocrine research
Safety & Tolerability
88/100
Generally well-tolerated in controlled studies
PK / PD
Plasma t½ (SC; Kisspeptin analogs)
GnRH Pulse Activation
LH / FSH Response
Reproductive Axis Signaling
Mechanism & Testing

Identity: Kisspeptin (KISS1-derived peptide), supplied as a 10mg lyophilized research peptide used in neuroendocrine and reproductive-axis studies.

Mode:
• Activates KISS1R (GPR54) receptors in the hypothalamus.
• Directly stimulates GnRH neurons, increasing pulsatile GnRH output.
• Downstream effects include elevations in LH and FSH in controlled models.
• Studied for roles in puberty onset, reproductive hormone balance, fertility investigations, and metabolic-endocrine integration.

Analytics: HPLC purity verification; LC-MS/MS identity; sequence confirmation; endotoxin via LAL; solubility/appearance checks.
PD readouts: GnRH pulse frequency, LH/FSH secretion profiling, sex-hormone panels, reproductive-axis biomarkers, hypothalamic imaging markers.
Monitoring (research): hormone fluctuations, reproductive-axis sensitivity, local injection tolerance.

For educational/research-style product content. Not medical advice; not for human use.