WOLVERINE

Wolverine combines two research peptides—BPC-157 (a synthetic pentadecapeptide derived from gastric protein) and TB-500 (a synthetic fragment modeled on thymosin beta-4’s actin-binding domain). The stack is used in advanced experimental designs that explore cytoskeletal dynamics, angiogenic signaling, and extracellular-matrix (ECM) remodeling. Investigations commonly focus on tissue homeostasis, stress-response pathways, and cellular migration frameworks.

BPC-157: Reported to interact with growth-factor and nitric-oxide–linked pathways to support cytoprotection and endothelial function; research models evaluate effects on VEGF signaling, fibroblast activity, and ECM turnover.
TB-500 (Tβ4-fragment): Modeled on an actin-sequestering motif implicated in cell migration and cytoskeletal remodeling; preclinical systems assess impacts on lamellipodia formation, integrin dynamics, and re-epithelialization kinetics.
Stack Rationale: Parallel interrogation of endothelial/angiogenic signaling (BPC-157) and actin-driven cell migration programs (TB-500) to study coordinated phases of tissue remodeling in vitro and in vivo research settings.

Endothelial biology and angiogenesis assays • Fibroblast/keratinocyte migration models • ECM synthesis and remodeling studies • Cytoskeletal signaling (actin dynamics, focal adhesion turnover) • Stress-response and cytoprotection paradigms in translational research.

Revitalized Health peptides are produced under cGMP-aligned conditions with pharmaceutical-grade inputs. Each component (BPC-157 and TB-500) is confirmed at ≥99% purity via HPLC with identity verified by LC-MS/MS. Lots undergo appearance/solubility checks and microbial/endotoxin screening to research-grade specifications. Batch-specific Certificates of Analysis are available to document analytical methods and results.

Store lyophilized vials at 2–8 °C, protected from light and moisture. After reconstitution with bacteriostatic water, maintain at 2–8 °C and utilize within 20 days. Avoid repeated freeze–thaw cycles to preserve peptide integrity and receptor/target interaction fidelity.

For laboratory research use only. Not intended for human consumption, therapeutic, or diagnostic application. Supplied exclusively to qualified professionals conducting controlled scientific investigations.

Identity: Wolverine is a two-peptide stack combining BPC-157 (pentadecapeptide) with TB-500 (a thymosin β4–derived fragment associated with actin-mediated cell motility).
Mode: BPC-157: cytoprotective pro-repair signaling; supports endothelial migration and microvascular stability; influences FAK–paxillin/NO pathways and ECM collagen alignment in models. TB-500: linked to actin cytoskeleton modulation and cell migration, facilitating re-epithelialization and angiogenic sprouting; complementary to BPC-157’s ECM/vascular cues. Stack rationale: pair angiogenic/migratory cues with ECM organization to support tendon/ligament, soft-tissue, and microvascular repair phenotypes in preclinical systems.
Analytics: HPLC/LC-MS identity & purity for each peptide; peptide content and counter-ion profiling; sterility/endotoxin where applicable; stability (accelerated/real-time). PD (exploratory): ultrasound or MRI for tissue integrity, wound/tendon scoring, capillary density (IHC/CD31), cytokine & MMP/TIMP panels; functional measures (ROM/strength) in observational settings. Monitoring: ISR, GI tolerance (if oral), hypersensitivity history; avoid implying disease treatment.